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Adriana López-Dóriga is a statistician with a Master degree in Public Health and Epidemiology (UPF), a Master degree in Bioinformatics and Genetic Epidemiology coursed in UK, and a PhD in Medicine in Cancer and Human Genetics awarded by the University of Barcelona (UB). She has worked and managed data analysis in the Catalan Institute of Oncology (ICO) in various projects. She began with data management and statistical analysis in genetic epidemiology of colon and ovarian cancer, and after the Master in bioinformatics she was granted a fellowship from the Instituto de Salud Carlos III to work developing NGS data analysis pipelines for the diagnostics of hereditary cancer and research in colon cancer. At present, she works in NGS data analysis for different projects in the Biomarkers and Susceptibility Unit (UBS-ICO).
BIOINFORMATICS, BIOSTATISTICS, GENETIC EPIDEMIOLOGY, CANCER GENETICS, NEXT GENERATION SEQUENCING (NGS) ANALYSIS (DNA-SEQ, RNA-SEQ).

EDUCATION

2016 – PhD in Medicine, University of Barcelona (UB), Spain
2010 – Master in Bioinformatics and Genetic Epidemiology, University of Cardiff, Cardiff, UK.
2008 – Master in Public Health and Epidemiology, Pompeu Fabra University (UPF),Barcelona, Spain
2006 – Diploma in Statistics, Autonomous University of Barcelona (UAB), Barcelona, Spain

 

WORK EXPERIENCE

 

2014 – current: Bioinformatician at Unit of Biomarkers and Susceptibility (UBS), Catalan Institute of Oncology (ICO), Barcelona

2014: Lecturer of Biostatistics and Bioinformatics to Pharmacogenomics postgraduate students, University of Barcelona (UB), Barcelona

2013 – 2014: Lecturer of Biostatistics to graduate students of Economy and Business, Autonomous University of Barcelona (UAB), Barcelona

 2010 – 2013: Bioinformatician at Translational Research Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona

2006 – 2009: Data manager and statistician, Epidemiology and Research Cancer Unit, Catalan Institute of Oncology (ICO), Barcelona

 

 

SELECTED PUBLICATIONS

– Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer.Feliubadaló L, Tonda R, Gausachs M, Trotta JR, Castellanos E, López-Doriga A, Teulé À, Tornero E, Del Valle J, Gel B, Gut M, Pineda M, González S, Menéndez M, Navarro M, Capellá G, Gut I, Serra E, Brunet J, Beltran S, Lázaro C. Sci Rep. 2017 Jan 4;7:37984. doi: 10.1038/srep37984.

– Nanofluidic Digital PCR and Extended Genotyping of RAS and BRAF for Improved Selection of Metastatic Colorectal Cancer Patients for Anti-EGFR Therapies.Azuara D, Santos C, Lopez-Doriga A, Grasselli J, Nadal M, Sanjuan X, Marin F, Vidal J, Montal R, Moreno V, Bellosillo B, Argiles G, Elez E, Dienstmann R, Montagut C, Tabernero J, Capellá G, Salazar R. Mol Cancer Ther. 2016 May;15(5):1106-12.

– Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer.Sanz-Pamplona R, Lopez-Doriga A, Paré-Brunet L, Lázaro K, Bellido F, Alonso MH, Aussó S, Guinó E, Beltrán S, Castro-Giner F, Gut M, Sanjuan X, Closa A, Cordero D, Morón-Duran FD, Soriano A, Salazar R, Valle L, Moreno V. Clin Cancer Res. 2015 Oct 15;21(20):4709-18.

– ICO amplicon NGS data analysis: a Web tool for variant detection in common high-risk hereditary cancer genes analyzed by amplicon GS Junior next-generation sequencing.Lopez-Doriga A, Feliubadaló L, Menéndez M, Lopez-Doriga S, Morón-Duran FD, del Valle J, Tornero E, Montes E, Cuesta R, Campos O, Gómez C, Pineda M, González S, Moreno V, Capellá G, Lázaro C. Hum Mutat. 2014 Mar;35(3):271-7.

– Next-generation sequencing meets genetic diagnostics: development of a comprehensive workflow for the analysis of BRCA1 and BRCA2 genes.Feliubadaló L, Lopez-Doriga A, Castellsagué E, del Valle J, Menéndez M, Tornero E, Montes E, Cuesta R, Gómez C, Campos O, Pineda M, González S, Moreno V, Brunet J, Blanco I, Serra E, Capellá G, Lázaro C. Eur J Hum Genet. 2013 Aug;21(8):864-70.