Publicaciones 2024

1. Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction.

   Gauderman WJ, Fu Y, Queme B, Kawaguchi E, Wang Y, Morrison J, Brenner H, Chan A, Gruber SB, Keku T, Li L, Moreno V, Pellatt AJ, Peters U, Samadder NJ, Schmit SL, Ulrich CM, Um C, Wu A, Lewinger JP, Drew DA, Mi H. bioRxiv. 2024 Dec 19;(). doi: 10.1101/2024.12.16.628610. Epub: 2024 Dec 19. PMID: 39763728; PMCID: PMC11702571

2. Burden of postmenopausal breast cancer attributable to excess body weight: comparative study of body mass index and CUN-BAE in MCC-Spain study.

   Cubelos-Fernández N, Dávila-Batista V, Fernández-Villa T, Castaño-Vinyals G, Perez-Gomez B, Amiano P, Ardanaz E, Delgado Sillero I, Llorca J, Tardón GF, Alguacil J, Vanaclocha Espí M, Marcos-Gragera R, Moreno V, Aragones N, Dorronsoro A, Guevara M, Reguero Celada S, Pollan M, Kogevinas M, Martín V. J Epidemiol Community Health. 2024 Dec 10;79(1):64-71. doi: 10.1136/jech-2023-220706. Epub: 2024 Dec 10. PMID: 39419524; PMCID: PMC11671986

3. Hand Acceleration Time is a Valuable Ultrasonographic Tool in Hand Perfusion as Adjuvant Evaluation for Diagnosing Chronic Upper Limb Ischemia.

   Gonzalo B, Videla S, Moranas J, Carnaval T, Herranz C, Espinar E, Iborra E. Ann Vasc Surg. 2024 Dec;109():187-196. doi: 10.1016/j.avsg.2024.05.045. Epub: 2024 Jul 18. PMID: 39032595

4. Detection of germline CNVs from gene panel data: benchmarking the state of the art.

   Munté E, Roca C, Del Valle J, Feliubadaló L, Pineda M, Gel B, Castellanos E, Rivera B, Cordero D, Moreno V, Lázaro C, Moreno-Cabrera JM. Brief Bioinform. 2024 Nov 22;26(1). doi: 10.1093/bib/bbae645. PMID: 39668338; PMCID: PMC11637760

5. Multiomic integration analysis identifies atherogenic metabolites mediating between novel immune genes and cardiovascular risk.

   Carreras-Torres R, Galván-Femenía I, Farré X, Cortés B, Díez-Obrero V, Carreras A, Moratalla-Navarro F, Iraola-Guzmán S, Blay N, Obón-Santacana M, Moreno V, de Cid R. Genome Med. 2024 Oct 24;16(1):122. doi: 10.1186/s13073-024-01397-2. Epub: 2024 Oct 24. PMID: 39449064; PMCID: PMC11515386

6. Exploring the Chemopreventive Effect of Medication on Gene Expression Linked to Colorectal Cancer: An Observational and Mendelian Randomization Analysis in Healthy Colon Mucosa.

   Moratalla-Navarro F, Carreras-Torres R, Díez-Obrero V, Devall M, Obón-Santacana M, Díez-Villanueva A, Guinó E, Casey G, Li L, Moreno V. Int J Mol Sci. 2024 Oct 23;25(21). doi: 10.3390/ijms252111395. Epub: 2024 Oct 23. PMID: 39518949; PMCID: PMC11547083

7. Metagenomic Study Reveals Phage-Bacterial Interactome Dynamics in Gut and Oral Microbiota in Pancreatic Diseases.

   Vilà-Quintana L, Fort E, Pardo L, Albiol-Quer MT, Ortiz MR, Capdevila M, Feliu A, Bahí A, Llirós M, García-Velasco A, Morell Ginestà M, Laquente B, Pozas D, Moreno V, Garcia-Gil LJ, Duell EJ, Pimenoff VN, Carreras-Torres R, Aldeguer X. Int J Mol Sci. 2024 Oct 12;25(20). doi: 10.3390/ijms252010988. Epub: 2024 Oct 12. PMID: 39456772; PMCID: PMC11507633

8. Neoadjuvant sunitinib plus exemestane in post-menopausal women with hormone receptor-positive/HER2-negative early-stage breast cancer (SUT_EXE-08): a phase I/II trial.

   Fullana B, Morales S, Petit A, Alay A, Verdaguer H, Climent F, Navarro-Perez V, Cejuela M, Galvan P, Gumà A, Llombart-Cussac A, Cordero D, Casanovas O, Prat A, Gil-Gil M, Pernas S. Sci Rep. 2024 Oct 9;14(1):23626. doi: 10.1038/s41598-024-72152-1. Epub: 2024 Oct 9. PMID: 39384801; PMCID: PMC11464634

9. Differences in tumor-associated T-cell receptor repertoires between early-onset and average-onset colorectal cancer.

   Tsai YY, Nair KG, Barot SV, Xiang S, Kamath S, Melas M, Walker CP, Srivastava RM, Osborne N, Chan TA, Mitchem JB, Bonner JD, McDonnell KJ, Idos GE, Sanz-Pamplona R, Greenson JK, Rennert HS, Rennert G, Moreno V, Gruber SB, Khorana AA, Liska D, Schmit SL. J Natl Cancer Inst. 2024 Oct 1;116(10):1645-1653. doi: 10.1093/jnci/djae143. PMID: 38902947; PMCID: PMC12116298

10. Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer.

    McGee HM, Bonner JD, Egelston C, Fu Y, Flores OC, Lindsey S, Shaktah L, Moratalla-Navarro F, Kamal Y, Tsang K, Walker CP, Idos G, McDonnell KJ, Rennert H, Barry EL, Brenner H, Buchanan DD, Campbell PT, Chan AT, Chang-Claude J, Figueiredo JC, Gago-Dominguez M, Hoffmeister M, Hsu L, Huyghe JR, Jenkins MA, Le Marchand L, Lenz HJ, Li L, Lindblom A, Liu Ruby YR, Lynch BM, Newton CC, Offit K, Ogino S, Pamplona RS, Pellatt AJ, Pharoah PDP, Phipps A, Reynaga L, Templeton A, Um CY, Wolk A, Woods MO, Wu AH, Yun Y, Zheng W, Williams TM, Conti DV, Peters U, Lejbkowicz F, Greenson JK, Schmit SL, Gauderman WJ, Hamilton SR, Moreno V, Rennert G, Gruber SB. medRxiv. 2024 Sep 26;(). doi: 10.1101/2024.09.22.24314127. Epub: 2024 Sep 26. PMID: 39464256; PMCID: PMC11507956

11. Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors.

    Marcos-Delgado A, Martín-Sánchez V, Molina-Barceló A, Alonso-Molero J, Pérez-Gómez B, Pollán M, Aragonés N, Ederra-Sanza M, Fernández-Tardón G, Binefa G, Moreno V, Barrios-Rodríguez R, Amiano P, Huerta JM, Teso EP, Alguacil J, Castaño-Vinyals G, Kogevinas M, Molina de la Torre AJ. Healthcare (Basel). 2024 Sep 25;12(19). doi: 10.3390/healthcare12191917. Epub: 2024 Sep 25. PMID: 39408097; PMCID: PMC11475455

12. Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression.

    Amengual J, Alay A, Vaquero J, Gonzalez-Sanchez E, Bertran E, Sánchez A, Herrera B, Meyer K, Maus M, Serrano M, Martínez-Chantar ML, Fabregat I. Cell Death Dis. 2024 Sep 17;15(9):680. doi: 10.1038/s41419-024-07063-0. Epub: 2024 Sep 17. PMID: 39289337; PMCID: PMC11408630

13. Diet Impacts on Gene Expression in Healthy Colon Tissue: Insights from the BarcUVa-Seq Study.

    Obón-Santacana M, Moratalla-Navarro F, Guinó E, Carreras-Torres R, Díez-Obrero V, Bars-Cortina D, Ibáñez-Sanz G, Rodríguez-Alonso L, Mata A, García-Rodríguez A, Devall M, Casey G, Li L, Moreno V. Nutrients. 2024 Sep 16;16(18). doi: 10.3390/nu16183131. Epub: 2024 Sep 16. PMID: 39339731; PMCID: PMC11434945

14. Sex-specific chrono-nutritional patterns and association with body weight in a general population in Spain (GCAT study).

    Pons-Muzzo L, de Cid R, Obón-Santacana M, Straif K, Papantoniou K, Santonja I, Kogevinas M, Palomar-Cros A, Lassale C. Int J Behav Nutr Phys Act. 2024 Sep 12;21(1):102. doi: 10.1186/s12966-024-01639-x. Epub: 2024 Sep 12. PMID: 39267095; PMCID: PMC11396659

15. Dietary Pattern's Role in Hepatic Epigenetic and Dietary Recommendations for the Prevention of NAFLD.

    Martín Barraza JI, Bars-Cortina D. Nutrients. 2024 Sep 3;16(17). doi: 10.3390/nu16172956. Epub: 2024 Sep 3. PMID: 39275272; PMCID: PMC11396970

16. Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing.

    Aglago EK, Qu C, Harlid S, Phipps AI, Steinfelder RS, Ogino S, Thomas CE, Hsu L, Toland AE, Brenner H, Berndt SI, Buchanan DD, Campbell PT, Cao Y, Chan AT, Drew DA, Figueiredo JC, French AJ, Gallinger S, Georgeson P, Giannakis M, Goode EL, Gruber SB, Gunter MJ, Harrison TA, Hoffmeister M, Huang WY, Hullar MA, Huyghe JR, Jenkins MA, Lynch BM, Moreno V, Murphy N, Newton CC, Nowak JA, Obón-Santacana M, Sun W, Ugai T, Um CY, Zaidi SH, Tsilidis KK, van Guelpen B, Peters U. Am J Clin Nutr. 2024 Sep;120(3):664-673. doi: 10.1016/j.ajcnut.2024.07.012. Epub: 2024 Jul 16. PMID: 39025327; PMCID: PMC11393398

17. The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche.

    Gonzalez-Sanchez E, Vaquero J, Caballero-Diaz D, Grzelak J, Fusté NP, Bertran E, Amengual J, Garcia-Saez J, Martín-Mur B, Gut M, Esteve-Codina A, Alay A, Coulouarn C, Calero-Perez S, Valdecantos P, Valverde AM, Sánchez A, Herrera B, Fabregat I. J Pathol. 2024 Aug;263(4-5):482-495. doi: 10.1002/path.6299. Epub: 2024 Jun 14. PMID: 38872438

18. Comparison between 16S rRNA and shotgun sequencing in colorectal cancer, advanced colorectal lesions, and healthy human gut microbiota.

    Bars-Cortina D, Ramon E, Rius-Sansalvador B, Guinó E, Garcia-Serrano A, Mach N, Khannous-Lleiffe O, Saus E, Gabaldón T, Ibáñez-Sanz G, Rodríguez-Alonso L, Mata A, García-Rodríguez A, Obón-Santacana M, Moreno V. BMC Genomics. 2024 Jul 29;25(1):730. doi: 10.1186/s12864-024-10621-7. Epub: 2024 Jul 29. PMID: 39075388; PMCID: PMC11285316

19. SpadaHC: a database to improve the classification of variants in hereditary cancer genes in the Spanish population.

    Moreno-Cabrera JM, Feliubadaló L, Pineda M, Prada-Dacasa P, Ramos-Muntada M, Del Valle J, Brunet J, Gel B, Currás-Freixes M, Calsina B, Salazar-Hidalgo ME, Rodríguez-Balada M, Roig B, Fernández-Castillejo S, Durán Domínguez M, Arranz Ledo M, Infante Sanz M, Castillejo A, Dámaso E, Soto JL, de Miguel M, Hidalgo Calero B, Sánchez-Zapardiel JM, Ramon Y Cajal T, Lasa A, Gisbert-Beamud A, López-Novo A, Ruiz-Ponte C, Potrony M, Álvarez-Mora MI, Osorio A, Lorda-Sánchez I, Robledo M, Cascón A, Ruiz A, Spataro N, Hernan I, Borràs E, Moles-Fernández A, Earl J, Cadiñanos J, Sánchez-Heras AB, Bigas A, Capellá G, Lázaro C. Database (Oxford). 2024 Jul 4;2024(). doi: 10.1093/database/baae055. PMID: 38965703; PMCID: PMC11223915

20. Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews.

    Plans-Beriso E, Babb-de-Villiers C, Petrova D, Barahona-López C, Diez-Echave P, Hernández OR, Fernández-Martínez NF, Turner H, García-Ovejero E, Craciun O, Fernández-Navarro P, Fernández-Larrea N, García-Esquinas E, Kuhn I, Jiménez-Planet V, Moreno V, Rodríguez-Artalejo F, Sánchez MJ, Pollan-Santamaria M, Blackburn L, Kroese M, Pérez-Gómez B. Syst Rev. 2024 Jun 1;13(1):147. doi: 10.1186/s13643-024-02554-9. Epub: 2024 Jun 1. PMID: 38824585; PMCID: PMC11143646

21. Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer.

    Laskar RS, Qu C, Huyghe JR, Harrison T, Hayes RB, Cao Y, Campbell PT, Steinfelder R, Talukdar FR, Brenner H, Ogino S, Brendt S, Bishop DT, Buchanan DD, Chan AT, Cotterchio M, Gruber SB, Gsur A, van Guelpen B, Jenkins MA, Keku TO, Lynch BM, Le Marchand L, Martin RM, McCarthy K, Moreno V, Pearlman R, Song M, Tsilidis KK, Vodička P, Woods MO, Wu K, Hsu L, Gunter MJ, Peters U, Murphy N, Colorectal Transdisciplinary (CORECT) Study, the Colon Cancer Family Registry (CCFR), Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). Ann Oncol. 2024 Jun;35(6):523-536. doi: 10.1016/j.annonc.2024.02.008. Epub: 2024 Feb 24. PMID: 38408508; PMCID: PMC11213623

22. Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk.

    Tian Y, Lin Y, Qu C, Arndt V, Baurley JW, Berndt SI, Bien SA, Bishop DT, Brenner H, Buchanan DD, Budiarto A, Campbell PT, Carreras-Torres R, Casey G, Chan AT, Chen R, Chen X, Conti DV, Díez-Obrero V, Dimou N, Drew DA, Figueiredo JC, Gallinger S, Giles GG, Gruber SB, Gunter MJ, Harlid S, Harrison TA, Hidaka A, Hoffmeister M, Huyghe JR, Jenkins MA, Jordahl KM, Joshi AD, Keku TO, Kawaguchi E, Kim AE, Kundaje A, Larsson SC, Marchand LL, Lewinger JP, Li L, Moreno V, Morrison J, Murphy N, Nan H, Nassir R, Newcomb PA, Obón-Santacana M, Ogino S, Ose J, Pardamean B, Pellatt AJ, Peoples AR, Platz EA, Potter JD, Prentice RL, Rennert G, Ruiz-Narvaez EA, Sakoda LC, Schoen RE, Shcherbina A, Stern MC, Su YR, Thibodeau SN, Thomas DC, Tsilidis KK, van Duijnhoven FJB, Van Guelpen B, Visvanathan K, White E, Wolk A, Woods MO, Wu AH, Peters U, Gauderman WJ, Hsu L, Chang-Claude J. Br J Cancer. 2024 Jun;130(10):1687-1696. doi: 10.1038/s41416-024-02638-2. Epub: 2024 Apr 1. PMID: 38561434; PMCID: PMC11091089

23. Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer.

    Papadimitriou N, Kim A, Kawaguchi ES, Morrison J, Diez-Obrero V, Albanes D, Berndt SI, Bézieau S, Bien SA, Bishop DT, Bouras E, Brenner H, Buchanan DD, Campbell PT, Carreras-Torres R, Chan AT, Chang-Claude J, Conti DV, Devall MA, Dimou N, Drew DA, Gruber SB, Harrison TA, Hoffmeister M, Huyghe JR, Joshi AD, Keku TO, Kundaje A, Küry S, Le Marchand L, Lewinger JP, Li L, Lynch BM, Moreno V, Newton CC, Obón-Santacana M, Ose J, Pellatt AJ, Peoples AR, Platz EA, Qu C, Rennert G, Ruiz-Narvaez E, Shcherbina A, Stern MC, Su YR, Thomas DC, Thomas CE, Tian Y, Tsilidis KK, Ulrich CM, Um CY, Visvanathan K, Wang J, White E, Woods MO, Schmit SL, Macrae F, Potter JD, Hopper JL, Peters U, Murphy N, Hsu L, Gunter MJ, Gauderman WJ. EBioMedicine. 2024 Jun;104():105146. doi: 10.1016/j.ebiom.2024.105146. Epub: 2024 May 14. PMID: 38749303; PMCID: PMC11112268

24. Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer.

    Drew DA, Kim AE, Lin Y, Qu C, Morrison J, Lewinger JP, Kawaguchi E, Wang J, Fu Y, Zemlianskaia N, Díez-Obrero V, Bien SA, Dimou N, Albanes D, Baurley JW, Wu AH, Buchanan DD, Potter JD, Prentice RL, Harlid S, Arndt V, Barry EL, Berndt SI, Bouras E, Brenner H, Budiarto A, Burnett-Hartman A, Campbell PT, Carreras-Torres R, Casey G, Chang-Claude J, Conti DV, Devall MAM, Figueiredo JC, Gruber SB, Gsur A, Gunter MJ, Harrison TA, Hidaka A, Hoffmeister M, Huyghe JR, Jenkins MA, Jordahl KM, Kundaje A, Le Marchand L, Li L, Lynch BM, Murphy N, Nassir R, Newcomb PA, Newton CC, Obón-Santacana M, Ogino S, Ose J, Pai RK, Palmer JR, Papadimitriou N, Pardamean B, Pellatt AJ, Peoples AR, Platz EA, Rennert G, Ruiz-Narvaez E, Sakoda LC, Scacheri PC, Schmit SL, Schoen RE, Stern MC, Su YR, Thomas DC, Tian Y, Tsilidis KK, Ulrich CM, Um CY, van Duijnhoven FJB, Van Guelpen B, White E, Hsu L, Moreno V, Peters U, Chan AT, Gauderman WJ. Sci Adv. 2024 May 31;10(22):eadk3121. doi: 10.1126/sciadv.adk3121. Epub: 2024 May 29. PMID: 38809988; PMCID: PMC11135391

25. Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention and intervention.

    Li Q, Song Q, Chen Z, Choi J, Moreno V, Ping J, Wen W, Li C, Shu X, Yan J, Shu XO, Cai Q, Long J, Huyghe JR, Pai R, Gruber SB, Casey G, Wang X, Toriola AT, Li L, Singh B, Lau KS, Zhou L, Wu C, Peters U, Zheng W, Long Q, Yin Z, Guo X. medRxiv. 2024 May 31;(). doi: 10.1101/2024.05.29.24308170. Epub: 2024 May 31. PMID: 38853880; PMCID: PMC11160851

26. dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe.

    Rodrigues JS, Chenlo M, Bravo SB, Perez-Romero S, Suarez-Fariña M, Sobrino T, Sanz-Pamplona R, González-Prieto R, Blanco Freire MN, Nogueiras R, López M, Fugazzola L, Cameselle-Teijeiro JM, Alvarez CV. Nat Commun. 2024 May 14;15(1):3736. doi: 10.1038/s41467-024-47751-1. Epub: 2024 May 14. PMID: 38744818; PMCID: PMC11094195

27. Comparing Data from Three Satellites on Artificial Light at Night (ALAN): Focusing on Blue Light's Influence on Colorectal Cancer in a Case-Control Study in Spain.

    Harding BN, Palomar-Cros A, Valentín A, Espinosa A, Sánchez de Miguel A, Castaño-Vinyals G, Pollán M, Perez B, Moreno V, Kogevinas M. Environ Health Perspect. 2024 May;132(5):57702. doi: 10.1289/EHP14414. Epub: 2024 May 17. PMID: 38758117; PMCID: PMC11100459

28. Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.

    Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Peña N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzón M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, Walczak H. Cell Death Differ. 2024 May;31(5):544-557. doi: 10.1038/s41418-024-01278-6. Epub: 2024 Mar 21. PMID: 38514848; PMCID: PMC11093991

29. Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes.

    Chen Z, Guo X, Tao R, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Ping J, Jia G, Long J, Li C, Shen Q, Xie Y, Timofeeva MN, Thomas M, Schmit SL, Díez-Obrero V, Devall M, Moratalla-Navarro F, Fernandez-Tajes J, Palles C, Sherwood K, Briggs SEW, Svinti V, Donnelly K, Farrington SM, Blackmur J, Vaughan-Shaw PG, Shu XO, Lu Y, Broderick P, Studd J, Harrison TA, Conti DV, Schumacher FR, Melas M, Rennert G, Obón-Santacana M, Martín-Sánchez V, Oh JH, Kim J, Jee SH, Jung KJ, Kweon SS, Shin MH, Shin A, Ahn YO, Kim DH, Oze I, Wen W, Matsuo K, Matsuda K, Tanikawa C, Ren Z, Gao YT, Jia WH, Hopper JL, Jenkins MA, Win AK, Pai RK, Figueiredo JC, Haile RW, Gallinger S, Woods MO, Newcomb PA, Duggan D, Cheadle JP, Kaplan R, Kerr R, Kerr D, Kirac I, Böhm J, Mecklin JP, Jousilahti P, Knekt P, Aaltonen LA, Rissanen H, Pukkala E, Eriksson JG, Cajuso T, Hänninen U, Kondelin J, Palin K, Tanskanen T, Renkonen-Sinisalo L, Männistö S, Albanes D, Weinstein SJ, Ruiz-Narvaez E, Palmer JR, Buchanan DD, Platz EA, Visvanathan K, Ulrich CM, Siegel E, Brezina S, Gsur A, Campbell PT, Chang-Claude J, Hoffmeister M, Brenner H, Slattery ML, Potter JD, Tsilidis KK, Schulze MB, Gunter MJ, Murphy N, Castells A, Castellví-Bel S, Moreira L, Arndt V, Shcherbina A, Bishop DT, Giles GG, Southey MC, Idos GE, McDonnell KJ, Abu-Ful Z, Greenson JK, Shulman K, Lejbkowicz F, Offit K, Su YR, Steinfelder R, Keku TO, van Guelpen B, Hudson TJ, Hampel H, Pearlman R, Berndt SI, Hayes RB, Martinez ME, Thomas SS, Pharoah PDP, Larsson SC, Yen Y, Lenz HJ, White E, Li L, Doheny KF, Pugh E, Shelford T, Chan AT, Cruz-Correa M, Lindblom A, Hunter DJ, Joshi AD, Schafmayer C, Scacheri PC, Kundaje A, Schoen RE, Hampe J, Stadler ZK, Vodicka P, Vodickova L, Vymetalkova V, Edlund CK, Gauderman WJ, Shibata D, Toland A, Markowitz S, Kim A, Chanock SJ, van Duijnhoven F, Feskens EJM, Sakoda LC, Gago-Dominguez M, Wolk A, Pardini B, FitzGerald LM, Lee SC, Ogino S, Bien SA, Kooperberg C, Li CI, Lin Y, Prentice R, Qu C, Bézieau S, Yamaji T, Sawada N, Iwasaki M, Le Marchand L, Wu AH, Qu C, McNeil CE, Coetzee G, Hayward C, Deary IJ, Harris SE, Theodoratou E, Reid S, Walker M, Ooi LY, Lau KS, Zhao H, Hsu L, Cai Q, Dunlop MG, Gruber SB, Houlston RS, Moreno V, Casey G, Peters U, Tomlinson I, Zheng W. Nat Commun. 2024 Apr 26;15(1):3557. doi: 10.1038/s41467-024-47399-x. Epub: 2024 Apr 26. PMID: 38670944; PMCID: PMC11053150

30. Germline genetic regulation of the colorectal tumor immune microenvironment.

    Schmit SL, Tsai YY, Bonner JD, Sanz-Pamplona R, Joshi AD, Ugai T, Lindsey SS, Melas M, McDonnell KJ, Idos GE, Walker CP, Qu C, Kast WM, Da Silva DM, Glickman JN, Chan AT, Giannakis M, Nowak JA, Rennert HS, Robins HS, Ogino S, Greenson JK, Moreno V, Rennert G, Gruber SB. BMC Genomics. 2024 Apr 25;25(1):409. doi: 10.1186/s12864-024-10295-1. Epub: 2024 Apr 25. PMID: 38664626; PMCID: PMC11046907

31. Tissue-specific genetic variation suggests distinct molecular pathways between body shape phenotypes and colorectal cancer.

    Peruchet-Noray L, Sedlmeier AM, Dimou N, Baurecht H, Fervers B, Fontvieille E, Konzok J, Tsilidis KK, Christakoudi S, Jansana A, Cordova R, Bohmann P, Stein MJ, Weber A, Bézieau S, Brenner H, Chan AT, Cheng I, Figueiredo JC, Garcia-Etxebarria K, Moreno V, Newton CC, Schmit SL, Song M, Ulrich CM, Ferrari P, Viallon V, Carreras-Torres R, Gunter MJ, Freisling H. Sci Adv. 2024 Apr 19;10(16):eadj1987. doi: 10.1126/sciadv.adj1987. Epub: 2024 Apr 19. PMID: 38640244; PMCID: PMC11029802

32. Exploring the Associations of Inflammatory and Oxidative Stress Biomarkers with Pancreatic Diseases: An Observational and Mendelian Randomisation Study.

    Vilà-Quintana L, Fort E, Pardo L, Albiol-Quer MT, Ortiz MR, Capdevila M, Feliu A, Bahí A, Llirós M, Aguilar E, García-Velasco A, Ginestà MM, Laquente B, Pozas D, Lluansí A, Pimenoff VN, Moreno V, Garcia-Gil LJ, Duell EJ, Carreras-Torres R, Aldeguer X. J Clin Med. 2024 Apr 12;13(8). doi: 10.3390/jcm13082247. Epub: 2024 Apr 12. PMID: 38673519; PMCID: PMC11050604

33. Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature.

    Thomas CE, Georgeson P, Qu C, Steinfelder RS, Buchanan DD, Song M, Harrison TA, Um CY, Hullar MA, Jenkins MA, Van Guelpen B, Lynch BM, Melaku YA, Huyghe JR, Aglago EK, Berndt SI, Boardman LA, Campbell PT, Cao Y, Chan AT, Drew DA, Figueiredo JC, French AJ, Giannakis M, Goode EL, Gruber SB, Gsur A, Gunter MJ, Hoffmeister M, Hsu L, Huang WY, Moreno V, Murphy N, Newcomb PA, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Sun W, Toland AE, Trinh QM, Ugai T, Zaidi SH, Peters U, Phipps AI. Cancer Epidemiol Biomarkers Prev. 2024 Apr 3;33(4):534-546. doi: 10.1158/1055-9965.EPI-23-0600. PMID: 38252034; PMCID: PMC10990777

34. Toenail zinc and risk of prostate cancer in the MCC-Spain case-control study.

    Gutiérrez-González E, Pastor-Barriuso R, Castelló A, Castaño-Vinyals G, Fernández de Larrea-Baz N, Dierssen-Sotos T, Jiménez-Moleón JJ, Molina-Barceló A, Fernández-Tardón G, Zumel-Marne Á, Moreno V, Gómez-Ariza JL, Sierra MÁ, García-Barrera T, Espinosa A, Plans-Beriso E, Gómez-Acebo I, Aragonés N, Kogevinas M, Pollán M, Pérez-Gómez B. Environ Res. 2024 Mar 15;245():118065. doi: 10.1016/j.envres.2023.118065. Epub: 2023 Dec 28. PMID: 38159663

35. Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses.

    Papadimitriou N, Qu C, Harrison TA, Bever AM, Martin RM, Tsilidis KK, Newcomb PA, Thibodeau SN, Newton CC, Um CY, Obón-Santacana M, Moreno V, Brenner H, Mandic M, Chang-Claude J, Hoffmeister M, Pellatt AJ, Schoen RE, Harlid S, Ogino S, Ugai T, Buchanan DD, Lynch BM, Gruber SB, Cao Y, Hsu L, Huyghe JR, Lin Y, Steinfelder RS, Sun W, Van Guelpen B, Zaidi SH, Toland AE, Berndt SI, Huang WY, Aglago EK, Drew DA, French AJ, Georgeson P, Giannakis M, Hullar M, Nowak JA, Thomas CE, Le Marchand L, Cheng I, Gallinger S, Jenkins MA, Gunter MJ, Campbell PT, Peters U, Song M, Phipps AI, Murphy N. EBioMedicine. 2024 Mar;101():105010. doi: 10.1016/j.ebiom.2024.105010. Epub: 2024 Feb 12. PMID: 38350331; PMCID: PMC10874711

36. Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk.

    Stern MC, Sanchez Mendez J, Kim AE, Obón-Santacana M, Moratalla-Navarro F, Martín V, Moreno V, Lin Y, Bien SA, Qu C, Su YR, White E, Harrison TA, Huyghe JR, Tangen CM, Newcomb PA, Phipps AI, Thomas CE, Kawaguchi ES, Lewinger JP, Morrison JL, Conti DV, Wang J, Thomas DC, Platz EA, Visvanathan K, Keku TO, Newton CC, Um CY, Kundaje A, Shcherbina A, Murphy N, Gunter MJ, Dimou N, Papadimitriou N, Bézieau S, van Duijnhoven FJB, Männistö S, Rennert G, Wolk A, Hoffmeister M, Brenner H, Chang-Claude J, Tian Y, Le Marchand L, Cotterchio M, Tsilidis KK, Bishop DT, Melaku YA, Lynch BM, Buchanan DD, Ulrich CM, Ose J, Peoples AR, Pellatt AJ, Li L, Devall MAM, Campbell PT, Albanes D, Weinstein SJ, Berndt SI, Gruber SB, Ruiz-Narvaez E, Song M, Joshi AD, Drew DA, Petrick JL, Chan AT, Giannakis M, Peters U, Hsu L, Gauderman WJ. Cancer Epidemiol Biomarkers Prev. 2024 Mar 1;33(3):400-410. doi: 10.1158/1055-9965.EPI-23-0717. PMID: 38112776; PMCID: PMC11343583

37. Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications.

    Hijazo-Pechero S, Alay A, Cordero D, Marín R, Vilariño N, Palmero R, Brenes J, Montalban-Casafont A, Nadal E, Solé X. Mol Oncol. 2024 Feb;18(2):453-470. doi: 10.1002/1878-0261.13550. Epub: 2023 Dec 21. PMID: 37943164; PMCID: PMC10850798

38. Artificial intelligence methods to estimate overall mortality and non-relapse mortality following allogeneic HCT in the modern era: an EBMT-TCWP study.

    Mussetti A, Rius-Sansalvador B, Moreno V, Peczynski C, Polge E, Galimard JE, Kröger N, Blaise D, Peffault de Latour R, Kulagin A, Mousavi A, Stelljes M, Hamladji RM, Middeke JM, Salmenniemi U, Sengeloev H, Forcade E, Platzbecker U, Reményi P, Angelucci E, Chevallier P, Yakoub-Agha I, Craddock C, Ciceri F, Schroeder T, Aljurf M, Ch K, Moiseev I, Penack O, Schoemans H, Mohty M, Glass B, Sureda A, Basak G, Peric Z. Bone Marrow Transplant. 2024 Feb;59(2):232-238. doi: 10.1038/s41409-023-02147-5. Epub: 2023 Nov 25. PMID: 38007531

39. Bayesian Analysis of the ICAT·COVID Randomized Clinical Trial.

    Malchair P, Villoria J, Giol J, Jacob J, Carnaval T, Videla S. Clin Ther. 2024 Feb;46(2):176-180. doi: 10.1016/j.clinthera.2023.11.010. Epub: 2023 Dec 10. PMID: 38072752

40. Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.

    Georgeson P, Steinfelder RS, Harrison TA, Pope BJ, Zaidi SH, Qu C, Lin Y, Joo JE, Mahmood K, Clendenning M, Walker R, Aglago EK, Berndt SI, Brenner H, Campbell PT, Cao Y, Chan AT, Chang-Claude J, Dimou N, Doheny KF, Drew DA, Figueiredo JC, French AJ, Gallinger S, Giannakis M, Giles GG, Goode EL, Gruber SB, Gsur A, Gunter MJ, Harlid S, Hoffmeister M, Hsu L, Huang WY, Huyghe JR, Manson JE, Moreno V, Murphy N, Nassir R, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Pai RK, Papadimitrou N, Potter JD, Schoen RE, Song M, Sun W, Toland AE, Trinh QM, Tsilidis K, Ugai T, Um CY, Macrae FA, Rosty C, Hudson TJ, Winship IM, Phipps AI, Jenkins MA, Peters U, Buchanan DD. medRxiv. 2024 Jan 30;(). doi: 10.1101/2023.03.10.23287127. Epub: 2024 Jan 30. PMID: 37090539; PMCID: PMC10120801

41. Performance of a Shotgun Prediction Model for Colorectal Cancer When Using 16S rRNA Sequencing Data.

    Ramon E, Obón-Santacana M, Khannous-Lleiffe O, Saus E, Gabaldón T, Guinó E, Bars-Cortina D, Ibáñez-Sanz G, Rodríguez-Alonso L, Mata A, García-Rodríguez A, Moreno V. Int J Mol Sci. 2024 Jan 18;25(2). doi: 10.3390/ijms25021181. Epub: 2024 Jan 18. PMID: 38256252; PMCID: PMC10816515

42. Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation.

    Chen Z, Song W, Shu XO, Wen W, Devall M, Dampier C, Moratalla-Navarro F, Cai Q, Long J, Van Kaer L, Wu L, Huyghe JR, Thomas M, Hsu L, Woods MO, Albanes D, Buchanan DD, Gsur A, Hoffmeister M, Vodicka P, Wolk A, Marchand LL, Wu AH, Phipps AI, Moreno V, Ulrike P, Zheng W, Casey G, Guo X. J Natl Cancer Inst. 2024 Jan 10;116(1):127-137. doi: 10.1093/jnci/djad178. PMID: 37632791; PMCID: PMC10777674

43. Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study.

    Constantinescu AE, Bull CJ, Jones N, Mitchell R, Burrows K, Dimou N, Bézieau S, Brenner H, Buchanan DD, D'Amato M, Jenkins MA, Moreno V, Pai RK, Um CY, White E, Murphy N, Gunter M, Timpson NJ, Huyghe JR, Vincent EE. Int J Cancer. 2024 Jan 1;154(1):94-103. doi: 10.1002/ijc.34691. Epub: 2023 Aug 14. PMID: 37578112; PMCID: PMC10864681

44. Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study.

    Watts EL, Gonzales TI, Strain T, Saint-Maurice PF, Bishop DT, Chanock SJ, Johansson M, Keku TO, Le Marchand L, Moreno V, Newcomb PA, Newton CC, Pai RK, Purdue MP, Ulrich CM, Smith-Byrne K, Van Guelpen B, PRACTICAL consortium, CRUK, BPC3, CAPS, PEGASUS, Day FR, Wijndaele K, Wareham NJ, Matthews CE, Moore SC, Brage S. Br J Cancer. 2024 Jan;130(1):114-124. doi: 10.1038/s41416-023-02489-3. Epub: 2023 Dec 6. PMID: 38057395; PMCID: PMC10781786