Publications 2026

  1. Implementing a molecular prescreening strategy for tumors without public NGS access in a cancer center network: Results from the PREICO project.
    Sàbat P, Ajenjo-Bauza M, Hierro C, Ruffinelli JC, Gil-Martin M, Ochoa-de-Olza M, Bergamino M, Calvo M, Soto-Castillo JJ, Fina C, Llop S, Stradella A, Oliva M, Notario L, Carcereny E, Teixidor-Vilà E, Domènech M, Jové M, Villanueva R, Alay A, Azuara D, González-Acosta M, Otero-Torres S, Gausachs M, Varela M, Villatoro S, Solanes A, Teulé A, Cuadra C, Moreno V, Nadal E, Cordero D, Lázaro C, Martin-Liberal J. Eur J Cancer. 2026 May 15;239():116728. doi: 10.1016/j.ejca.2026.116728. Epub: 2026 Apr 4. PMID: 41962211
  2. Optimizing GRIDSS for clinical use: A targeted NGS filtering strategy for germline structural variant detection.
    Munté E, Rofes P, Millán-Castillo M, Solanes A, Muñoz X, Campos O, Alay A, Ajenjo-Bauza M, Navarro E, de la Morena-Barrio B, Salinas M, Vargas-Parra G, Cuesta R, Moreno-Cabrera JM, Cordero D, Pineda M, Del Valle J, Lázaro C, Feliubadaló L. Eur J Hum Genet. 2026 Mar 16;(). doi: 10.1038/s41431-026-02016-x. Epub: 2026 Mar 16. PMID: 41840221
  3. Association between arsenic levels in toenails and urine and prostate cancer risk: Findings from the MCC-Spain study.
    Varea-Jiménez E, Pastor-Barriuso R, Sierra Á, Dierssen-Sotos T, Fernández Tardón G, Aragonés N, Gómez-Acebo I, Castaño-Vinyals G, Gómez-Ariza JL, Kogevinas M, Moreno V, Fernández-Navarro P, Pollán M, Pérez-Gómez B, García-Esquinas E. Environ Res. 2026 Mar 15;293():123767. doi: 10.1016/j.envres.2026.123767. Epub: 2026 Jan 12. PMID: 41534579
  4. HLA Heterozygosity Influences Colorectal Cancer Risk and Survival Outcome.
    Tsai YY, Thomas CE, Law PJ, Chen Z, Gruber SB, Schmit SL, International Colorectal Cancer GWAS Collaborative. Gastroenterology. 2026 Mar;170(3):619-622. doi: 10.1053/j.gastro.2025.10.020. Epub: 2026 Jan 20. PMID: 41556857; PMCID: PMC13010477
  5. Genetic risk factors modulate the association between physical activity and colorectal cancer.
    Peoples AR, Obón-Santacana M, Kim AE, Kawaguchi ES, Fu Y, Qu C, Moratalla-Navarro F, Morrison J, Lin Y, Arndt V, Berndt SI, Bien SA, Bishop DT, Bouras E, Brenner H, Buchanan DD, Campbell PT, Chan AT, Chang-Claude J, Conti DV, Corley DA, Devall MA, Dimou N, Drew DA, Gruber SB, Gunter MJ, Harlid S, Harrison TA, Hoffmeister M, Hsu L, Huyghe JR, Keku TO, Kundaje A, Lewinger JP, Li L, Lynch BM, Le Marchand L, Martín V, Murphy N, Newton CC, Ogino S, Hardikar S, Ose J, Pai RK, Palmer JR, Papadimitriou N, Pardamean B, Pellatt AJ, Pinchev M, Platz EA, Potter JD, Rennert G, Ruiz-Narvaez EA, Sakoda LC, Schoen RE, Shcherbina A, Stern MC, Su YR, Thomas CE, Tian Y, Tsilidis KK, Um CY, van Duijnhoven FJB, Van Guelpen B, Visvanathan K, Wang J, White E, Wolk A, Woods MO, Wu AH, Ulrich CM, Peters U, Gauderman WJ, Moreno V. BMC Med. 2026 Feb 5;24(1). doi: 10.1186/s12916-026-04675-5. Epub: 2026 Feb 5. PMID: 41645200; PMCID: PMC12973902
  6. The endonuclease MCPIP1 protects against liver cancer development in a sex-dependent manner by modulating B-catenin and CREB1.
    Kwapisz O, Marona P, Gorka J, Myrczek R, Gonzalez-Sanchez E, Bertran E, Kotlinowski J, Gluc M, Alay A, Pydyn N, Kujdowicz M, Ramos E, Fabregat I, Miekus K. JHEP Rep. 2026 Jan 29;8(5):101755. doi: 10.1016/j.jhepr.2026.101755. Epub: 2026 Jan 29. PMID: 41955682; PMCID: PMC13091202
  7. Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility.
    Chen Z, Song W, Li Q, Li C, Wen W, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Timofeeva MN, Thomas M, Schmit SL, Martin V, Devall M, Dampier C, Moratalla-Navarro F, Cai Q, Wang J, Shi J, Kweon SS, Tanikawa C, Jia WH, Shu X, Long J, Gao J, Kim J, Shin A, Matsuo K, Jee SH, Jung KJ, Wang N, Kim DH, Ping J, Yang G, Shin MH, Ren Z, Oh JH, Oze I, Ahn YO, Gao YT, Pan ZZ, Kamatani Y, Van Kaer L, Wu L, Li B, Matsuda K, Shu XO, Hsu L, Dunlop MG, Gruber SB, Houlston R, Tomlinson I, Li L, Lau KS, Moreno V, Casey G, Peters U, Zheng W, Guo X. Nat Commun. 2026 Jan 15;17(1):1377. doi: 10.1038/s41467-025-68127-z. Epub: 2026 Jan 15. PMID: 41540004; PMCID: PMC12877115
  8. Genome-wide interaction analysis of long-term trihalomethane exposure in drinking water and colorectal cancer risk in a Spanish Multicenter Case-Control Study (MCC-Spain).
    Moratalla-Navarro F, Obón-Santacana M, Rius-Sansalvador B, Guinó E, Moragas N, Donat-Vargas C, de Larrea-Baz NF, Molina-Barceló A, Guevara M, Morón-Duran FD, Dierssen-Sotos T, Tardón A, Castaño-Vinyals G, Cabrera-Castro N, Molina AJ, Aizpurua A, Morales-Suárez-Varela MM, Martín V, Fernández-Navarro P, Villanueva CM, Moreno V. Environ Int. 2026 Jan 11;207():110059. doi: 10.1016/j.envint.2026.110059. Epub: 2026 Jan 11. PMID: 41544563
  9. Investigating the Causal Effect of Potential Therapeutic Agents for Colorectal Cancer Prevention: A Mendelian Randomization Analysis.
    Fryer E, Bishop DT, Campbell PT, Chan AT, Le Marchand L, Li CI, Moreno V, Gunter MJ, Phipps AI, Grant RC, Schmit SL, Martin RM, Yarmolinsky J, Haycock P. Cancer Epidemiol Biomarkers Prev. 2026 Jan 9;35(1):95-108. doi: 10.1158/1055-9965.EPI-25-0875. Epub: 2025 oct 14. PMID: 41085561; PMCID: PMC7618373
  10. Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention.
    Li Q, Song Q, Chen Z, Choi J, Moreno V, Ping J, Wen W, Li C, Shu X, Yan J, Shu XO, Cai Q, Long J, Huyghe JR, Pai R, Gruber SB, Yang Y, Casey G, Wang X, Toriola AT, Li L, Singh B, Lau KS, Zhou L, Zhang Z, Wu C, Peters U, Zheng W, Long Q, Yin Z, Guo X. Am J Hum Genet. 2026 Jan 8;113(1):41-56. doi: 10.1016/j.ajhg.2025.11.008. Epub: 2025 Dec 2. PMID: 41338217
  11. ClinBioNGS: A Clinical Bioinformatics Pipeline for Integrated Analysis of Somatic Next-Generation Sequencing Cancer Panels.
    Marín R, Alay A, Ajenjo-Bauza M, Hijazo-Pechero S, Montironi C, Hernández-Illán E, Jares P, Azuara D, Varela M, Vidal A, Puig-Butillé JA, Lázaro C, Moreno V, Cordero D, Nadal E, Solé X. JCO Clin Cancer Inform. 2026 Jan;10():e2500221. doi: 10.1200/CCI-25-00221. Epub: 2026 Jan 8. PMID: 41505665